P5P+

$70.00

Neuroendocrine Support^‡

$0.70/day · 90-day supply

A multi-pathway formula designed to support healthy neuroendocrine function, neurotransmitter production, cognitive performance, and a healthy stress response.^‡

Featuring active vitamin B6 as P5P, rhodiola, ginkgo, L-tyrosine, apigenin, and triacetyluridine, P5P+ combines cofactors, adaptogens, botanical extracts, and nutrient precursors that support mental clarity, stress resilience, and healthy neurotransmitter pathways.^‡

A clean, capsule-based formula tested for purity, potency, and contaminants. Built for daily foundational neuroendocrine support.

Per Serving

10mg Vitamin E (as D-Alpha Tocopheryl Succinate)
50mg Vitamin B6 (as Pyridoxal-5-Phosphate) (P5P)
5mg Zinc (as Zinc Bisglycinate)
300mg Rhodiola Extract (Rhodiola Rosea) (root) (3% Rosavins, 1% Salidrosides)
60mg Ginkgo Extract (Ginkgo Biloba) (leaf) (24% Ginkgo Flavone Glycosides)
125mg L-Tyrosine
50mg Apigenin
25mg Uridine (as Triacetyluridine)

How to Take

Take one (1) capsule daily with food, or as recommended by your healthcare professional.

The Science

P5P+ was designed around nutrients and botanicals that support neurotransmitter synthesis, cognitive function, mental performance, and a healthy stress response.^‡ P5P is the active coenzyme form of vitamin B6 and supports enzyme pathways involved in neurotransmitter production, while rhodiola, ginkgo, L-tyrosine, apigenin, and triacetyluridine provide complementary support for stress resilience, cognitive function, and neuroendocrine health.^‡

P5P and neurotransmitter-related enzyme pathways
Review discussing pyridoxal-5-phosphate as the active form of vitamin B6 and its role as a cofactor in metabolic and neurotransmitter-related enzyme pathways.
PMID: 22201923
Vitamin B6 and neurotransmitter synthesis
Review discussing vitamin B6 physiology, including PLP-dependent pathways involved in neurotransmitter synthesis.
PMCID: PMC4288272
Rhodiola and stress resilience
Review of clinical evidence evaluating Rhodiola rosea preparations in stress, fatigue, and mental performance contexts.
PMID: 35745023
Ginkgo and cognitive support
Review evaluating Ginkgo biloba for cognitive improvement in healthy individuals.
PMCID: PMC6513461
Apigenin and neurotransmitter receptor pathways
Study evaluating apigenin’s interaction with GABAergic and glutamatergic receptor signaling pathways.
PMID: 15464088
Uridine and synaptic membrane support
Study discussing uridine as a circulating precursor involved in synaptic membrane phosphatide pathways.
PMID: 19262950